#$%^&*AU2020220146A120200910.pdf#####Abstract An ophthalmic composition, comprising: 4-(3-amino-1-(isoquinolin-6-ylamino )-1-oxopropan2-yl)benzyl 2,4- dimethylbenzoate or its pharmaceutically acceptable salts; about 0.01 % weight/volume to about 1.0% weight/volume of a buffer; and about 0.01 % weight/volume to about 10% weight/volume of a tonicity agent.