Michael Ohlmeyer;Goutham Narla;Neil Dhawan;David Kastrinsky
发明人:
Michael Ohlmeyer,Goutham Narla,Neil Dhawan,David Kastrinsky
申请号:
US14238511
公开号:
US09540358B2
申请日:
2012.08.16
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Tricyclic chemical modulators of FOXO transcription factor proteins are disclosed. The compounds are useful to treat cancer, age-onset proteotoxicity, stress-induced depression, inflammation, and acne. The compounds are of the following phenothiazine, dibenzoazepine and annulene and similar genera: