Shuntaro OKA,Masaru KANAGAWA,Masahiro ONO,Yoshihiro DOI
申请号:
US15445532
公开号:
US20170265441A1
申请日:
2017.02.28
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Provided is a method for producing an animal model of osteoblastic bone metastasis. A non-human animal in which an osteoblastic lesion is formed in a wide range has been successfully produced with a probability of 100% by: administering a calcineurin inhibitor to a non-human animal; and injecting a tumor cell into an artery or a vein of the non-human animal, wherein the non-human animal and the tumor cell are in an allogeneic or xenogeneic relation.