A system and methodare provided that employ a monitoringdevice to monitor at least one patientphysiological response to a Changein temperature of the patient (e.g.pursuant to induced hypothermiatherapy), wherein a monitoring signalis provided by the monitoring device.In turn, an output (e.g. a visual and/orauditory output) may be providedto a user indicative of at least onemeasure of Patient response to thechange in temperature. Alternativelyor additionally, a processor may beprovided to process the monitoringsignal provide an output employableby medical personnel to control apatient shivering response to thepatient temperature change. Suchinformation may comprise informationregarding one or more anti-shiveringmedicament(s), e.g. correspondingdosage and/or frequency informationfor use by medical personnel in theadministration of the anti-shiveringmedicament.