Derek T. Chalmers,James B. Jones,Robert H. Spencer
申请号：
US14403535
公开号：
US20150150935A1
申请日:
2013.06.05
申请国别(地区):
US
年份:
2015
代理人:
摘要：
A method of treating of a mammalian subject suffering from an inflammatory disease or condition by administering a peripherally-restricted kappa opioid receptor agonist for reducing the inflammation is provided. The peripherally-restricted kappa opioid receptor agonist can include a peptide and the peptide can include D-amino acids. Administration of peripherally-restricted kappa opioid receptor agonists results in lowering of serum levels of pro-inflammatory cytokines and elevation of levels of anti-inflammatory cytokines.
