Disclosed is a brain electrode lead anchoring device comprising a cranial burr hole grommet which includes a cranial burr hole junction portion for anchoring the cranial burr hole grommet on the cranial burr hole with the inner wall of the cranial burr hole junction portion forming an electrode aperture through which a brain electrode lead passes and a cranial burr hole plug which has at least one groove for the passing through and anchoring of the brain electrode lead and which is arranged in the electrode aperture to close the electrode aperture. Compared with the prior art after the electrode lead reaches the designated target by means of a lead guiding needle a doctor pulls out the lead guiding needle and at this time the cranial burr hole plug immediately holds and clips tightly the electrode lead such that the electrode does not move in a horizontal direction or a vertical direction anchoring the electrode lead securely and accurately at the designated target position and avoiding the phenomenon of target deviation from occurring during the operation process to close the cranial burr hole grommet by the doctor. The height of the cranial burr hole plug does not exceed that of the cranial burr hole grommet such that the feeling of discomfort by the patient is avoided and the appearance is not affected.
