REGENERON PHARMACEUTICALS, INC.;THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
发明人:
KANDEL, JESSICA,HOLASH, JOCELYN,YAMASHIRO, DARRELL,HUANG, JIANZHONG,YANCOPOULOS, GEORGE,RUDGE, JOHN
申请号:
CA2519875
公开号:
CA2519875C
申请日:
2004.06.04
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
Methods of regressing or inhibiting a tumor in a subject by administering anagent capable of blocking, inhibiting, or ameliorating vascular endothelialgrowth factor (VEGF)-mediated activity to a subject in need thereof such thatthe tumor is regressed or inhibited. The method of the invention results in areduction of tumor size and inhibition of tumor metastases. This method isparticularly useful for patients suffering from bulky, metastatic cancers.