Robert MANGUSO;William N. HAINING;Dana-Farber Cancer Institute, Inc.
发明人:
William N. Haining,Robert Manguso
申请号：
US16629169
公开号：
US20200149042A1
申请日:
2018.07.16
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates, in part, to methods of treating a cancer in a subject comprising administering to the subject a therapeutically effective amount of an agent that inhibits one or more biomarkers listed in Table 1, such as regulators of ubiquitin proteasome pathway (e.g., STIP1 homology and U-Box containing protein 1 (STUB 1), ubiquilin-1 (UBQLN1), and heat shock protein 90 kDa beta member 1 (HSP90B 1)), in combination with an immunotherapy.
