Ju-man Song,Seon-Gi Min,Seung-Soo Lee,Do-min Lee,Kyung-Hwa Park,Moon-Chan Hwang,Bong-Ki Shin,Jong-Tae Je
申请号：
US15743769
公开号：
US10473666B2
申请日:
2016.07.18
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention relates to dye compounds represented by Formulae I and II, which are described in the specification. The dye compounds of the present invention have markedly improved quantum yields and emit strong fluorescence compared to existing cyanine dyes. Due to these advantages, the dye compounds of the present invention can find applications in various fields, for example, as probes for various biological systems where optical imaging is required. Particularly, the dye compounds of the present invention can be used as mitotrackers capable of labeling and tracking mitochondria. Therefore, the dye compounds of the present invention can be used to quantitatively image mitochondria in live tissues and cells. Furthermore, the dye compounds of the present invention can be applied as pH probes for measuring the pH of live cells.
