The present invention provides a lotion preparation that has antimicrobialpropertiesand also has elevated stability of the active ingredient. The preparationcontains no additiveswith safety problems.The lotion preparation contains a lotion preparation comprising (a) 1-cyclopropyl-8-methyl-7-[5-methyl-6-(methylamino)-3-pyridyl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acidand/or a pharmaceutically acceptable salt thereof, (b) at least one of ethanoland isopropanol,(c) a water-soluble cellulose derivative, and (d) 1 ,3-butylene glycol, andwherein thepreparation has a pH of 9 to 12