Claim 1: a compound of the formula (1): - B represents a double Bond or a Ring W CH = CH, insustituido or substituted with one or more tRepresents a phenyl group or an Aromatic heterocycle of 5 or 6 members, comprising at least one hetero Atom selected from the group consisting of o, N, N, S, (r\u00b3)S (OR) or s (OR) \u2082 r\u00b9 represents a Heterocyclic 5 or 6 members, total or partially unsaturated, aromatic, insustituido or substituted with one or more t\u00b9,Bonded to carbon comprising at least one nitrogen Atom R\u00b2 represents so\u2083h,Cfhco\u2082h represents Hydrogen or cf\u2082co\u2082h r\u00b3 independently - (ch\u2082) \u2098 - CN - (\u2099oc ch\u2082) (o) - (\u2098 q\u00b9 ch\u2082) - C (o) - (oq\u00b9 ch\u2082) \u2099 OC - (OR) - (oq\u00b9 ch\u2082) \u2099 OC - (OR) - nq\u00b9q\u00b2 (\u2098 ch\u2082) - C (o) - (nq\u00b9q\u00b2 \u2098 ch\u2082) - C (o) - (nq\u00b9oq\u00b2 ch\u2082) \u2098 NQ - C (o)Nq\u00b9q\u00b2 (- 1 - ch\u2082 \u2099 nq\u00b9c) - (OR) - (q\u00b2 ch\u2082 \u2099 nq\u00b9c) - (OR) - (oq\u00b2 ch\u2082 \u2099 nq\u00b9c) - (OR) - (\u2099oq\u00b9 nq\u00b9q\u00b2 ch\u2082) (\u2099nq\u00b9q\u00b2 ch\u2082) (ch\u2082) \u2099 - NH - C (nhq\u00b3) nq\u2074 (ch\u2082 = - - - ch = NH) \u2099 nq\u00b3 - (ch\u2082 \u2098) - C (= nq\u2074 nhq\u00b3) - (alkyl) - c\u2081\u208b\u2086 (and) - fluoroalquilo c\u2081\u208b\u2086 (cycloalkyl) - - - - c\u2083\u208b\u2086 (and) ciclofluoroalquilo c\u2083\u208b\u2086 (-) - (-) - \u209a ch\u2082) (y) - (ch\u2082) \u209aoc (or q\u00b9) (y) - (\u209a ch\u2082) - C (o) - oq\u00b9 (and) - (ch\u2082) \u209a - OC (or oq\u00b9 () - and (-) - ch\u2082 \u209a (OC) or (and) nq\u00b9q\u00b2 -) - (\u209a ch\u2082) - C (o) - nq\u00b9q\u00b2 (and) - (\u209a ch\u2082) - C (o)Nq\u00b9oq\u00b2 (-) - (\u209a ch\u2082) - C (o) - nq\u00b9q\u00b2 nq\u00b9 (-) - (ch\u2082) \u209a - nq\u00b9c (or q\u00b2 () - and (-) - ch\u2082) \u209a nq\u00b9c (or oq\u00b2 () - and (-) - ch\u2082 \u209a nq\u00b9c () nq\u00b9q\u00b2 - (OR) c