A fixing structure of bone screws and a connecting rod for a minimally invasive surgery contains: a rigid sleeve having a receiving space, two slots, and a through hole, the receiving space and the through hole being defined on two ends of the rigid sleeve, and the two slots being formed on two opposite sides of an outer wall of the rigid sleeve and communicate with the receiving space a flexible column being circular and retained in the receiving space of the rigid sleeve. Thereby, a complete rigid limitation and partial flexible limitations generate between at least one bone screw, hence only a tiny opening is cut in the minimally invasive surgery to facilitate surgery recovery and to lower infection risk.