Beth Israel Deaconess Medical Center;The General Hospital Corporation D/B/A;Dana Farber Cancer Institute
发明人:
Cantley, Lewis C.,Janne, Pasi A.,Engelman, Jeffrey
申请号：
AU2008239594
公开号：
AU2008239594B2
申请日:
2008.04.11
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
Provided herein are methods for treating cancer that is resistant to treatmentwith an anti- ErbB therapeutic agent and which is associated with an activatingMET gene mutation or a MET gene amplification. The methods involve administeringto a subject a combination of an anti- ErbB therapeutic and an anti-MET therapeutic.Also provided are methods for reducing ErbB mediated signaling or PI3 kinasemediated signaling in a cancer cell.
