Systems and methods for physical authentication of medical devices during wireless pairing are disclosed herein. The method can include receiving a request to initiate coupling. Following the request, a visual identifier can be generated with a light source. The visual identifier can include embedded data used to couple the medical devices. The visual identifier can be captured in image data, which image data can be analyzed and the embedded data can be extracted from the image data. Based on the embedded data that is extracted from the image data, secure coupling between medical devices can be established.