Cristianne Johanna Ferdinand RIJCKEN,Josephus Johannes WETERINGS,Johannes Bernardus Maria WIT
申请号:
US15777391
公开号:
US20190298855A1
申请日:
2016.11.18
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention is directed to particle comprising a drug and a ligand, and to method of making them and use thereof. Particularly, the present invention results in the covalent entrapment of drug(s) in high amounts in polymer carriers, such as (nano)particle, microspheres and other types of polymer devices for controlled release. The polymer carriers or devices can be decorated with ligands, allowing for targeting specific tissues and/or (non-) invasive monitoring.