Marshall Summar,Juan Cabrera-Luque,Gary Cunningham,Dione T. Kobayashi,James G. McArthur
申请号：
US15212009
公开号：
US20170106054A1
申请日:
2016.07.15
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention provides compositions and methods of treating hyperphenylalaninemia (e.g., phenylketonuria) in a subject in need thereof comprising administering to the subject an effective amount of a phenylalanine dehydrogenase (PheDH) polypeptide. The present invention also provides pharmaceutical formulations comprising PheDH for lowering the phenylalanine concentration in the subject (e.g., in the intestines and/or blood).
