植物におけるタンパク質のジスルフィド結合形成を阻害する方法
- 专利权人:
- 独立行政法人農業生物資源研究所
- 发明人:
- 川越 靖,恩田 弥生
- 申请号：
- JP2007051398
- 公开号：
- JP5067688B2
- 申请日:
- 2007.03.01
- 申请国别(地区):
- JP
- 年份:
- 2012
- 代理人:
- 摘要：
PROBLEM TO BE SOLVED: To provide a method for exhaustively inhibiting the disulfide bond formation of an intracellular protein and/or a method for inhibiting the oxidation activity of PDI (protein disulfide isomerase), comprising suppressing the expression of endogenous Ero1 gene in plant cells, and to provide a DNA having a function of suppressing the expression of Ero1 gene.
SOLUTION: A transformant in which the expression of Ero1 gene of rice plant is endosperm-specifically suppressed is prepared using an RNA interference. As a result of the analysis of the transformant of the RNA interference, the expression of Ero1 gene is suppressed to find the inhibition of protein disulfide bond formation.
COPYRIGHT: (C)2008,JPO&INPIT
- 来源网站：
- 中国工程科技知识中心
