Disintegrin variants and pharmaceutical uses thereof

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专利权人:

National Cheng Kung University

发明人:

Woei-Jer Chuang

申请号：

US15505357

公开号：

US10508137B2

申请日:

2015.08.21

申请国别(地区):

US

年份:

2019

代理人:

摘要：

Disintegrin variants that bind specifically to one or more of α5β1 and αv integrins, such as αvβ1, αvβ3, αvβ5, αvβ6 and αvβ8, but with reduced binding activity to αIIbβ3, are described. Also described are uses of the disintegrin variants for the treatment or prevention of a disease associated with an αv integrin or an α5β1 integrin.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/