HACHTEL STEPHANIE,WOHLFART PAULUS,WESTON JOHN,MÜLLER MARCO,DEFOSSA ELISABETH,MERTSCH KATHARINA,WENG JIAN-HUI,BINNIE ROBERT A.,ABDUL-LATIF FARID,BOCK WILLIAM JEROME,WALSER ARMIN,WENG JIAN-
申请号：
PL13763087
公开号：
PL2897939T3
申请日:
2013.09.19
申请国别(地区):
PL
年份:
2017
代理人:
摘要：
The present invention relates to benzoimidazole-carboxylic acid amide compounds of the formula I, in which R&prime；, R&Prime；, R&prime；&Prime；, R1, R2, R3, R4, R5, R6 and Z are defined as indicated below. The compounds of the formula I are APJ receptor modulators, and are useful for the treatment of diseases associated with increased blood pressure for example. The invention furthermore relates to the use of compounds of the formula I, in particular as active ingredients in pharmaceuticals, and pharmaceutical compositions comprising them.
