DERIVES DE PYRIMIDINE ET COMPOSITIONS UTILES EN TANT QU'INHIBITEURS DES KINASES C-KIT ET PDGFR

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专利权人:

IRM LLC

发明人:

LI, XIAOLIN,LIU, XIAODONG,MOLTENI, VALENTINA

申请号：

CA2686378

公开号：

CA2686378C

申请日:

2008.05.01

申请国别(地区):

CA

年份:

2012

代理人:

摘要：

The invention provides a novel class of compounds, pharmaceutical compositionscomprising such compounds and methods of using such compounds to treat orprevent diseasesor disorders associated with abnormal or deregulated kinase activity,particularly diseases ordisorders that involve abnormal activation of c-kit, PDGFR.alpha. andPDGFR.beta. kinases. Suchpyrimidine derivatives are of the Formula(see above formula)in which L is a 5 member heteroaryl ring containing 3 nitrogen atoms.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/