PROBLEM TO BE SOLVED: To provide an inhibitor for Wnt signaling route.SOLUTION: The present invention provides a compound represented by formula I, and a composition comprising the compound (X-Xindependently represent CRor N； Yis H or C (R)； Yand Yindependently represent H, halogen or C (R)； Rand Rindependently represent H, halogen, Calkyl, quinolinyl or the like； Rs independently represent H, halogen, cyano, Calkyl or the like； Rs independently represent H, halogen, cyano, Calkoxy or the like).SELECTED DRAWING: None【課題】Wntシグナル伝達経路の阻害剤。【解決手段】式Iで表される化合物、並びに該化合物を含む組成物。（X1～X8は夫々独立にCR4又はN；Y1はＨ又はC（R4）3；Y2及びY3は夫々独立にＨ、ハロゲン又はC（R3）3；R1及びR2は夫々独立にＨ、ハロゲン、C1-6アルキル、キノリニル等；R3は夫々独立にＨ、ハロゲン、シアノ、C1-6アルキル等；R4は夫々独立にＨ、ハロゲン、シアノ、C1-6アルコキシ等）【選択図】なし
