The pharmaceutical or nutraceutical composition with sustained release of an active ingredient according to the present invention comprises at least one coated granule; the coated granule being composed of a particle that comprises said active ingredient and is coated with at least two coatings that comprise a combination of excipients. The present invention relates also to a process for the preparation of the composition.持續釋放本發明活性成份之醫藥或營養組合物係包括至少一種包膜顆粒;該包膜顆粒係由包含該活性成份之粒子所組成並以至少二種包含賦形劑組合物之膜衣所塗覆。;本發明亦關於製備該組合物之方法。