USE OF INDOLE DERIVATIVES AS NURR-1 ACTIVATORS FOR THE TREATMENT OF MORBUS PARKINSON

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专利权人:

LABORATOIRES FOURNIER S.A.

发明人:

BOUBIA, BENAISSA,VAN VLIET, BERNARD,DEN HARTOG, JACOBUS,MCCREARY, ANDREW,TALLANDIER, MIREILLE,VAN DONGEN, MARIA,POUPARDIN-OLIVIER, OLIVIA

申请号：

AT09784501

公开号：

AT541831T

申请日:

2009.07.09

申请国别(地区):

AT

年份:

2012

代理人:

摘要：

The present invention relates to a compound derived from indole, especially a therapeutically useful compound, characterized in that it is selected from compounds of formula (I) in which R1 represents a halogen or a trifluoromethyl group, R2 represents a hydrogen atom or a C1-C4 alkyl group, R3 represents an isopropyl (1-methylethyl) group or a tert-butyl (1,1-dimethylethyl) group and n=3 or 4 and pharmaceutically acceptable salts of said compounds of formula (I). Application: Treatment of neurodegenerative diseases and more particularly of Parkinson's disease.

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