APGAR, JAMES REASONER JR,MADER, MICHELLE MARIE MM,PARRIS, KEVIN DELOS KD,.阿普加,.馬德,.帕理什
申请号:
HK15108889.0
公开号:
HK1208471A
申请日:
2015.09.11
申请国别(地区):
HK
年份:
2016
代理人:
摘要:
The disclosure provides improved neutralizing anti-GDF-8 antibodies capable of substantially higher levels of expression in host cells compared to previous anti-GDF-8 antibodies. Also provided are methods of using compositions comprising such antibodies to increase muscle mass or strength, and to treat or prevent muscular disorders, neuromuscular disorders, metabolic disorders, adipose tissue disorders or bone disorders.