To provide an active ingredient that can be blended in a skin external agent and an oral agent, has the effect of activating an epidermal cell and promoting epidermal cell protein synthesis, and is useful for improving the trouble of skin aging and rough skin, skin blotches and freckles, and morbid cells.SOLUTION: The present invention provides a composition containing Angelica acutiloba extract, Poria cocos extract, and Ziziphus jujuba extract, or a composition containing a mixture of Angelica acutiloba extract, Poria cocos extract, and Ziziphus jujuba extract, and yeast extract or a concentrated or dried product thereof.SELECTED DRAWING: None【課題】皮膚外用剤や経口用剤に配合可能であり、表皮細胞賦活効果及び表皮細胞タンパク質合成促進効果を有し、皮膚の老化や肌荒れ改善、シミ、ソバカスの改善、及び細胞の不健全化の改善に有用な有効成分の提供。【解決手段】トウキ(Angelica acutiloba)の抽出物、ブクリョウ(Poria cocos)の抽出物、及びナツメ(Ziziphus jujuba)の抽出物を含む組成物、又はトウキの抽出物、ブクリョウの抽出物、及びナツメの抽出物の混合物並びに酵母エキス又はその濃縮物若しくは乾燥物を含む組成物。【選択図】なし