It describes how to obtain nanoparticle adsorbents based on different GM3 type glycerol synthetic variants. According to the fine structure of the fatty acids in the synthesis of GM3 cerium, we can obtain adjustes that can stimulate humoral immune response or cellular antagonism to associated antigens. In particular, it also provides immunization ingredients, including peptides, peptides or proteins, as well as nanoparticles mentioned above.They are formed by dispersing the underwater proteins of Neisseria meningitis bacteria with a fully synthesized G3 Gangli variant in the outer membrane complex (cpme). 1. Property 1: adyuvante composed of nanoparticles formed by vari partnershipPreviously a complete synthesis of GM3 ganglios, it is now the water protein of the outer membrane complex of Neisseria meningitis Claim 4: vaccine components, including a nanoparticle adjust and a peptide antigen in any of the requirements of level 1-3Polypeptide or protein 13. Claim 5: the vaccine component of claim 4, which may include another adsorbent selected from the group: aluminum and oily adsorbent. Claim 8: the vaccine component of claim 4-6, wherein the antigen is pyrngrhm1 TT.Se describe la forma de obtener adyuvantes nano-particulados basados en diferentes variantes sintéticas del gangliósido GM3. En dependencia de la estructura fina del ácido graso presente en el ceramido del GM3 sintético, se pueden obtener adyuvantes que sirven para estimular específica y especializadamente la respuesta inmune humoral o la celular contra antígenos acompañantes. Particularmente, Además provee composiciones vacunales inmunogénicas que comprenden péptidos, polipéptidos o proteínas y las antes mencionadas nano-partículas, que se forman mediante la dispersión de proteínas hidrofóbicas del complejo de membrana externa (CPME) de la bacteria Neisseria meningitidis con variantes totalmente sintéticas del gangliósido GM3. Reivindicación 1: Un adyuvante que comprende nano-partículas formadas mediante
