PROBLEM TO BE SOLVED: To provide a new highly safe agent having sufficiently strong inhibitory actions on production of inflammatory cytokines such as TNF-&alpha and useful as an anti-inflammatory agent etc.SOLUTION: The inhibitor of inflammatory cytokine production in animal cells is characterized by comprising a compound represented by formula (1) (wherein, R1, R2 and R3 represent each a hydrogen atom or a hydroxy group) and a 16-22C unsaturated fatty acid or a glyceride thereof or a lower alkyl ester thereof as active ingredients.COPYRIGHT: (C)2008,JPO&INPIT【課題】安全性が高く、TNF-αなどの炎症性サイトカインの産生抑制作用が十分に強く、抗炎症剤等として有用な新規な薬剤を提供する。【解決手段】下記式(1)で示される化合物、及び炭素数16~22の不飽和脂肪酸若しくはそのグリセリド又は低級アルキルエステルを活性成分として含有することを特徴とする動物細胞における炎症性サイトカイン産生抑制剤。【選択図】なし
