The present invention provides, for example, the following: an aptamer having inhibitory activity on FGF2; a complex that includes an aptamer having bonding activity with and inhibitory activity on FGF2, and a functional substance (for example, an affinity substance, a labeling substance, an enzyme, a drug delivery medium, or a drug); and a medicine, a diagnostic drug, and a labeling agent that include an aptamer having bonding activity with and inhibitory activity on FGF2 or a complex which includes the aptamer and a functional substance.