University of Pittsburgh - Of the Commonwealth System of Higher Education
发明人:
William R. Wagner,Yasumoto Matsumura,Murugesan Velayutham,Yang Zhu
申请号:
US16336994
公开号:
US20190216847A1
申请日:
2017.10.06
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Provided herein are antioxidant, thermally-responsive copolymer-based compositions and methods of making and using the compositions, e.g., for treatment of ischemia reperfusion injury in a patient. The copolymer comprises a hydrocarbyl backbone, and a plurality of pendant pyrrolidone, antioxidant radical, polyester oligomer, and N-alkyl amide groups.