GYULA BEKE,EVA BOZO,SANDOR FARKAS,GYOERGY KESERUE,EVA SCHMIDT,EVA SZENTIRMAY,ISTVAN VAGO,MONIKA VASTAG,KATALIN HORNOK
申请号:
BRPI0718494
公开号:
BRPI0718494A2
申请日:
2007.10.27
申请国别(地区):
BR
年份:
2014
代理人:
摘要:
The present invention relates to new sulfonamide derivatives of formula (I) wherein R1-R8 and Z are as defined in the claims, and optical antipodes or racemates and/or salts and/or hydrates and/or solvates thereof, which are selective antagonists of bradykinin B1, to processes for producing these same compounds, pharmacological compositions containing them and to their use in therapy or prevention of painful and inflammatory conditions.