The present invention relates to an antibody-drug conjugate (ADC) and to a composition containing this conjugate for use for the treatment of cancer. The present invention provides, with respect to an ADC between a drug and an antibody specific for insoluble fibrin, an ADC wherein the linker connecting the antibody and the drug has a plasmin cleavage site, and also provides a pharmaceutical composition containing this ADC for use for the treatment of cancer.本發明係有關於一種抗體藥物複合體(ADC)及包含該複合體之供用於治療癌症的組成物。根據本發明,可提供一種在特殊針對不溶性纖維蛋白之抗體與藥物的ADC中,連結抗體與藥物之連結子具有胞漿素切斷序列的ADC及包含該ADC之供用於治療癌症的醫藥組成物。