Maria Gabriella Brasca,Tiziano Bandiera,Jay Aaron Bertrand,Paola Gnocchi,Danilo Mirizzi,Marcella Nesi,Achille Panzeri
申请号:
US14112559
公开号:
US09283224B2
申请日:
2012.04.05
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to substituted pyrimidinyl-pyrrole compounds of formula (I) which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity, in particular Janus kinases. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing such compounds or the pharmaceutical compositions containing them.