The present invention, and are useful in the prevention and treatment of eicosanoid-related diseases such as atopic dermatitis arteriosclerosis, diabetes, obesity, atherothrombosis, asthma, fever, pain, cancer, arthritis, or osteoarthritis pharmacological action excellent, the following equation with a physico-chemical properties, such as (I) [Each symbol in the formula, as described in the specification] to provide or a salt thereof. None [Selection Figure]本発明は、動脈硬化症、糖尿病、肥満、アテローム血栓症、喘息、発熱、疼痛、癌、リウマチ、変形性関節症またはアトピー性皮膚炎等のエイコサノイド関連疾患の予防・治療に有用であり、かつ優れた薬理作用、物理化学的性質等を有する下式(I)[式中の各記号は、明細書記載のとおり]で表される化合物またはその塩を提供する。【選択図】なし
