KYRATSOUS, CHRISTOS,MURPHY, ANDREW J.,WANG, CHENG,SABIN, LEAH
申请号:
CA3066947
公开号:
CA3066947A1
申请日:
2018.06.27
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
Provided herein are compositions and methods for retargeting recombinant viral capsid proteins/capsids/vectors, e.g., in vivo, with a multispecific binding molecule, such as a bispecific antibody, that specifically binds a heterologous epitope displayed by the capsid protein and a protein expressed on the cell of interest for the targeted delivery of a nucleotide of interest.