Systems and methods for digital X-ray imaging are disclosed. An example portable X-ray scanner includes: an X-ray detector configured to generate digital images based on incident X-ray radiation; an X-ray tube configured to output X-ray radiation; a computing device configured to control the X-ray tube, receive the digital images from the X-ray detector, and output the digital images to a display device; a power supply configured to provide power to the X-ray tube, the X-ray detector, and the computing device; and a frame configured to: hold the X-ray detector, the computing device, and the power supply; and hold the X-ray tube such that the X-ray tube directs the X-ray radiation to the X-ray detector.