REUTELINGSPERGER, CHRISTIAAN PETER MARIA,MOONEN, PETER JOZEF JACOBUS
申请号：
NZ59138809
公开号：
NZ591388A
申请日:
2009.08.26
申请国别(地区):
NZ
年份:
2012
代理人:
摘要：
Provides is a radiolabeled annexin, in which an annexin molecule comprises a minimum of 3 and a maximum of 10 histidine residues at its N-terminus, at least two of said histidine residues being adjacent or separated by no more than one other amino acid and being bound to a metal radionuclide, and in which the annexin molecule carries one or more cysteine residues at the concave side of the annexin molecule. Specific N-terminal sequences are also disclosed. The compounds can be used to image cell death in nucleated cells within a mammal in vivo.
