The present disclosure relates to a medicament delivery device comprising: a housing having a proximal and distal end; a medicament container positioned in the housing and having a medicament delivery member shield; a medicament delivery mechanism associated with the medicament container; an activation member operably connected to the medicament delivery mechanism and longitudinally movable in relation to the housing from an extended position to a retracted position to activate the medicament delivery mechanism; and a removable cap assembly comprising an outer tubular cap body and an inner tubular integrity lock member coaxially coupled to the outer tubular cap body; wherein in a first position of the removable cap assembly, a resilient structure of the inner tubular integrity lock member is engaged to a first engaging structure of the activation member and a second engaging structure of the housing for preventing the activation member from moving into the retracted position.本揭示內容有關藥物輸送裝置,包含:外殼,具有近側端及遠側端;藥物容器,被定位在該外殼中,且具有藥物輸送構件屏蔽件;藥物輸送機構,與該藥物容器有關聯;啟動構件,可操作地連接至該藥物輸送機構,並可關於該外殼由延伸位置縱向地運動至縮回位置,以啟動該藥物輸送機構;及可移除的蓋件組合體,包含外管狀蓋件本體及同軸向地耦接至該外管狀蓋件本體之內管狀完整性鎖構件;其中在該可移除蓋件組合體的第一位置中,該內管狀完整性鎖構件之彈性結構被嚙合該啟動構件的第一嚙合結構及該外殼之第二嚙合結構,用於防止該啟動構件運動進入該縮回位置。