The present invention provides a collyrium for preventing or treating dry eye syndrome containing cevimeline or a pharmaceutically acceptable salt thereof in a specific concentration. In addition, it is confirmed that the collyrium in a form of an aqueous solution containing cevimeline at a certain concentration has excellent stability when having a specific pH range, that is 6.0 to 7.5.본 발명은 세비메린 또는 이의 약학적으로 허용가능한 염을 특정 농도로 포함하는 안구 건조증의 예방 또는 치료용 점안제를 제공한다.