A diagnostic toothbrush comprising, in combination, a toothbrush body, a standard brush head containing toothbrush bristles for brushing teeth, a diagnostic brush head containing a transducer that can detect a dental pathology, and a camera brush head that can produce video images of dental and oral structures. The standard brush head, the diagnostic brush head and the camera brush head can be interchangeably mounted on the toothbrush body. Data from the diagnostic brush head is transferred to the toothbrush body when the diagnostic brush head is mounted on the toothbrush body, data from the camera brush head is transferred to the toothbrush body when the camera brush head is mounted on the toothbrush body, and the data from the diagnostic and camera brush heads is transmitted from the toothbrush body to a computing device.