COMPOSITIONS AND METHODS USING NMDA ANTAGONISTS TO ACHIEVE ANESTHETICS SAVING EFFECT.

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专利权人:

WYETH LLC

发明人:

CECIL MARK EPPLER,WILLIAM W. MUIR III,DAVID ROBERT HUSTEAD,THOMAS GERARD CULLEN,RAPHAEL JOHANNES GERHARDUS ZWIJNENBERG

申请号：

BRPI0815821

公开号：

BRPI0815821A2

申请日:

2008.08.26

申请国别(地区):

BR

年份:

2015

代理人:

摘要：

Provided herein are compositions, combinations, and methods comprising NMDA antagonists including, but not limited to, NMDA glutamate receptor antagonists such as [2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1-(7)-en-2-yl)alkyl]phosphonic acid and derivatives thereof, which are effective in reducing the amount of anesthetic required to maintain anesthesia (i.e. to achieve an anesthetic-sparing effect).

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