Methods of designing corneal implants, such as inlays, to compensate for a corneal response, such as epithelial remodeling of the epithelial layer, to the presence of the implant. Additionally, methods of performing alternative corneal vision correction procedures to compensate for an epithelial response to the procedure. Methods of compensating for a corneal response when performing a vision correction procedure to create a center near region of the cornea for near vision while providing distance vision peripheral to the central near zone.