Compositions Using Antibodies Directed to GPNMB and Uses Thereof

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专利权人:

发明人:

Michael E. Jeffers,William J. LaRochelle

申请号：

US15627694

公开号：

US20180043014A1

申请日:

2017.06.20

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present invention relates to antibodies, including fully human monoclonal antibodies, with specificity to GPNMB, and uses of such antibodies. The present invention further provides compositions that increase expression of GPNMB on the surface of tumor cells, and methods of using such compositions to increase the anti-cancer activity or other therapeutic efficacy of the antibodies and immunoconjugates provided herein.

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中国工程科技知识中心

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