Tae Young Roh,Seung-Jae Lee,Murat Artan,Yuna Kim,Hong Gil Nam
申请号：
US14882977
公开号：
US20170020116A1
申请日:
2015.10.14
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Provided are transgenic Caenorhabditis elegans (C. elegans) overexpressing DNA methyltransferase 3a (Dnmt3a) and a method of producing the same. According to the method, a specific mechanism and related factors for DNA methylation mediated by Dnmt3a may be found, and a critical gene for regulating the life span of C. elegans may be identified, and therefore C. elegans may be used as an animal model for screening a drug for a DNA methylation-related disease.
