Crystalline form Delta Salt of arginine perindoprilo; Preparation procedure; Pharmaceutical compositions containing it and its use for the treatment of cardiovascular diseases such as hypertension, heart failure or with stable coronary disease.
Delta crystalline form of perindopril L-arginine salt (I) having X-ray powder diffraction peaks measured using a diffractometer with a copper anticathode and expressed in terms of Bragg's angle 2 theta values as given in the specification, is new. Independent claims are included for: (1) the preparation of delta crystalline form of (I); and (2) a composition comprising an active agent and the delta crystalline form of (I) in combination with carriers. ACTIVITY : Cardiovascular-Gen; Hypotensive; Cardiant; Vasotropic. MECHANISM OF ACTION : Angiotensin I converting enzyme inhibitor.FORMA CRISTALINA DELTA DE LA SAL L-ARGININA DE PERINDOPRILO; PROCEDIMIENTO DE PREPARACION; COMPOSICIÓN FARMACEUTICA; Y USO EN EL TRATAMIENTO DE ENFERMEDADES CARDIOVASCULARES, TALES COMO HIPERTENSIPN ARTERIAL, INSUFICIENCIA CARDIACA O ENFERMEDAD CORONARIA ESTABLE.