The present invention provides a method wherein the method classifies a subject as suffering from dry eye the method consisting of: a. obtaining demographic data consisting of the age and gender of the subject; b. obtaining a tear sample from the patient and determining the level of human serum albumin; c. from the determined level of human serum albumin assigning a score for the determined amount of human serum albumin; and d. from the assigned score calculating a cutoff probability score according to the following equation: wherein the subject has dry eye if the calculated cutoff probability score is from 50% to 60%.