Rowan Andrew Grayling;Matthew Joseph Doyle;Begonia Y. Ho;Todd Laurence Underiner;Leo Timothy Laughlin
发明人:
Matthew Joseph Doyle,Leo Timothy Laughlin,Todd Laurence Underiner,Begonia Y. Ho,Rowan Andrew Grayling
申请号:
US11595530
公开号:
US08283135B2
申请日:
2006.11.10
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention encompasses topical oral care compositions comprising the combination of an anti-bacterial agent with an anti-inflammatory agent in an orally acceptable carrier for effective treatment and prevention of bacteria-mediated diseases and conditions in the oral cavity and for modulating host reaction to bacterial pathogens present in the oral cavity and to the toxins, endotoxins, inflammatory cytokines and mediators released by or prompted by these pathogens. The present invention also encompasses methods of use of these compositions comprising topical application to the oral cavity. The benefits of the present compositions and methods extend beyond treating and preventing oral bacterial infections in the oral cavity to promoting whole body or systemic health.