A disposable surgical drape is provided for use while performing surgical procedures on an eye of a patient, or other surgical procedures. There is an operative, surgical aperture formed through a base sheet for being located proximal to a first eye, or other surgical site, of the patient. An attachment zone is formed on the base sheet, proximal to the surgical aperture, and at least partially surrounds the surgical aperture. In one form, a guide extends across the surgical aperture on the upper surface of the base sheet. In another form, the base sheet has a non-surgical aperture spaced from the surgical aperture for being located proximal to a second eye of the patient. The disposable surgical drape can be provided in a folded form to facilitate placement on a patient and subsequent unfolding and spreading of the drape. In this embodiment, the drape includes a minimally-adhesive film that defines the surgical aperture.