The present invention provides a sterilization composition with synergism. The composition contains two effective components: A and B. The active component A is polyhexamethylene biguanidine hydrochloride or a salt compound acceptable in agriculture, the active component B is selected from one of cyprodinil, epoxiconazole, benthiavalicarb-isopropyl, zoxamide, azoxystrobin, prothioconazole, difenoconazole, fenamidone, polyoxin, iprodione, activated ester, dithianon, pyraclostrobin, trifloxystrobin, picoxystrobin, fluazinam, and thifluzamide or dimethomorph, and the weight ratio of the two components to one another is 1:50-50:1. The test result shows that, the sterilization composition provided by the present invention achieves obvious synergism, and more important, the application amount is reduced, and the use cost is decreased. By compounding bactericides with different mechanisms of action and different action manners, the application amount of each single bactericide is effectively reduced, thereby facilitating extension of the bacteriocidal spectrum, prolonging of the resistance to funguses, and improvement of the prevention and curing effect.La présente invention concerne une composition de stérilisation à synergisme. La composition contient deux constituants efficaces : A et B. Le constituant actif A est du chlorhydrate de polyhexaméthylène biguanidine ou un composé de type sel acceptable en agriculture, le constituant actif B est choisi parmi cyprodinil, époxiconazole, benthiavalicarb-isopropyle, zoxamide, azoxystrobine, prothioconazole, difénoconazole, fénamidone, polyoxine, iprodione, ester activé, dithianone, pyraclostrobine, trifloxystrobine, picoxystrobine, fluaziname, et thifluzamide ou diméthomorphe, et le rapport pondéral des deux constituants l'un par rapport à l'autre est de 1:50-50:1. Le résultat de test indique que la composition de stérilisation selon la présente invention réalise un synergisme évident, et plus important, que la quantité d'applic
