University Of Ulsan Foundation For Industry Cooperation
发明人:
申请号：
EP15860565.9
公开号：
EP3223016A1
申请日:
2015.07.29
申请国别(地区):
EP
年份:
2017
代理人:
摘要：
The present invention relates to a peptide for targeting gastric cancer, a composition for diagnosing radioresponsiveness-dependent gastric cancer using the peptide, and a drug delivery use of the peptide. A functional peptide capable of targeting cancer has been discovered so as to implement personalized diagnosis and treatment for individual patients having cancer, consideration of problems occurring during treatment in which treatment cases of respective patients differ due to different therapeutic responses resulting from genetic differences in the individual patients. After establishing animal models similar to cancer microenvironments of actual patients and dividing them into an irradiated population and a non-irradiated population as a control group, targeting efficiency has been tested for respective peptides selected by screening peptides specifically binding to the respective populations. As such, the present invention can be finally utilized in the technical development of image diagnosis for predicting responsiveness to radiotherapy, and accordingly, in the development of customized targeted therapeutic agents.
