Compounds and methods for modulating communication and virulence in quorum sensing bacteria

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专利权人:

Helen E. Blackwell

发明人:

Helen E. Blackwell,Grant D. Geske,Rachel Wezeman

申请号：

US12641056

公开号：

US08269024B2

申请日:

2009.12.17

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The present invention provides compositions and methods for modulating the communication and virulence of quorum sensing bacteria. In various exemplary embodiments, the invention provides a combinatorial library of quorum sensing compounds including synthetic analogs of naturally occurring and non-naturally occurring acyl-homoserine lactone (AHL) analogs, and methods of synthesizing and using these compounds.

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